Michael Jackson overdosed on a lethal level of the powerful anesthetic propofol when he died, a search warrant affidavit unsealed in Houston reportedly revealed Aug. 24.
He also may have had a powerful cocktail of several other sedatives coursing through his veins when his heart stopped June 25, according to Dr. Conrad Murray’s own account in the affidavit.
Murray told investigators he’d been trying to wean Jackson off the drug, fearing he might be developing an addiction, and administered a lower dose after having given MJ several other drugs in attempt to induce sleep the morning of June 25, according to the Los Angeles Times.
Murray lowered the dosage from the previous level of 50 milligrams to 25 milligrams and mixed it with two other sedatives, lorazepam and midazolam. On June 23, two days before Jackson’s death, he administered those two medications and withheld the propofol, the Times quoted from the affidavit.
The morning Jackson died, Murray tried to induce sleep without using propofol, according to the affidavit. The Times reports that Murray said he gave Jackson valium at 1:30 a.m. to no avail. At 2 a.m., he said, he injected lorazepam intravenously. And at 3 a.m., when Jackson was still awake, Murray administered midazolam.
Over the next few hours, Murray said he gave Jackson various drugs. Then at 10:40 a.m., Murray administered 25 milligrams of propofol after Jackson repeatedly demanded the drug, according to the court records.
In a post-mortem search of Jackson’s rented Holmby Hills estate, however, police detectives saw “about” eight bottles of propofol along with other vials and pills that had been prescribed to Jackson by Murray and two other doctors, including dermatologist Dr. Arnold Klein.
Murray told investigators he repeatedly asked the pop star what other physicians were treating Jackson and what drugs they were prescribing, MJ refused to provide that information.
The Los Angeles County Coroners Office has sealed Jackson’s official cause of death and autopsy report for the time being, presumably waiting on law enforcement agencies including the DEA to wrap up their probes.
Murray is already under a cloud of suspicion as police searched his homes, offices and pharmacy records for evidence that would point to a manslaughter charge in MJ’s death.